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Pharmacology – Introduction, Definition, Types

Pharmacology

Pharmacology is a branch of science about medicinal substances, called pharmaceuticals, or simply “drugs”. The field encompases drug composition,drug properties, interactions, toxicology, and desirable effects that can be used in therapy of diseases.

Greek : pharmacon – drug, logos – science.

Medication drugs have to be approved by drug regulatory authorities. This field is called regulatory affairs. The International Conference on Harmonisation works in the standardisation for this.

There are various classification systems for medicinal products including ATC classification.

Classes of medicinal products:

For the Gastrointestinal Tract

(see also Digestive system) antacid, reflux suppressant, antiflatulent, antidopaminergic, antispasmodic, proton pump inhibitor, cytoprotectant, prostaglandin analogue, laxative, antidiarrhoeal, colorectal agent, pancreatic enzyme, bile acids

For the Cardiovascular System

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ACE inhibitor, cardiac glycoside, phosphodiesterase inhibitor, nitrate, antiarrhythmic, Beta blocker, antianginal, diuretic, antihypertensive, Ca plus plus antagonist, Alpha blocker, vasodilator, antihistamine, peripheral activator, anticoagulant, heparin, antiplatelet drug, fibrinolytic, haemostatic drug, hypolipidaemic agent, statin.

For the Central Nervous System

hypnotic, anxiolytic, antipsychotic, antidepressant anti-emetic,anticonvulsant and antiepileptic, movement disorder drug, CNS stimulant barbiturate, tricyclic antidepressants, benzodiazepine, cyclopyrrolone, dopamine antagonist, antihistamine, anticholinergic, cannabinoids, 5HT antagonist, amphetamine, monoamine oxidase inhibitor, lithium salt,selective serotonin reuptake inhibitor

For Pain

analgesic, antipyretic, migraine treatment drug NSAIDs, opioid analgesic

For Musculo-Skeletal Disorders

NSAIDs, muscle relaxant, neuromuscular drug anticholinesterase

For Endocrine problems

androgen, antiandrogen, gonadotropin, corticosteroid, growth hormone,insulin, antidiabetic, thyroid hormones, antithyroid drugs, calcitonin, diphosponate, vasopressin analogues

For the Genito-Urinary System

antifungal, alkalising agent, quinolones, antibiotic, cholinergic, anticholinergic, anticholinesterase, antispasmodic, 5-Alpha reductaseinhibitor, selective Alpha 1 blocker

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For Infections and Infestations

antibiotic, antifungal, antileprotic, antituberculous drug, antimalarial,anthelmintic, amoebicide, antiviral, antiprotozoal

For Immunology

vaccine, immunoglobulin, immunosuppressant

For Nutrition

tonic, iron preparation, electrolyte, parenteral nutritional supplement, vitamins, anti-obesity drug, anabolic drug, haematopoietic drug, food product drug

For the Respiratory System

bronchodilator, NSAIDs, anti-allergic, antitussive, mucolytic, decongestant corticosteroid, Beta antagonist, anticholinergic, steroid

For the Ear, Nose and Oropharynx

sympathomimetic, antihistamine, anticholinergic, NSAIDs, steroid,antiseptic, local anesthetic, antifungal, cerumenolytic

For the Eye

anti-infective, topical antibiotic, astringent, NSAIDs, miotics, adrenergicneurone blocker, carbonic anhydrase inhibitor, ocular lubricant, mydriatic

For Allergic Disorders

anti-allergic, antihistamine, NSAIDs

For the Skin

emollient, anti-pruritic, antifungal, disinfectant, scabicide, pediculicide, tar products, vitamin A derivatives, vitamin D analogue, keratolytic, abrasive, systemic antibiotic, topical antibiotic, hormones, desloughingagent, exudate absorbant, fibrinolytic, proteolytic, sunscreen, antiperspirant

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For Contraception

contraceptive, oral contraceptives, contraceptive devices, spermicide, depot contraceptives

For Obstetrics and Gynaecology

NSAIDs, anticholinergic, haemostatic drug, antifibrinolytic, Hormone Replacement Therapy, bone regulator, Beta agonist, follicle stimulating hormone, luteinising hormone, LHRH gamolenic acid, gonadotropin release inhibitor, progestogen, dopamine agonist, oestrogen, prostaglandin, gonadorelin, clomiphene, tamoxifen, Diethylstilbestrol

For Neoplastc disorders

cytotoxic drug, sex hormones, aromatase inhibitor, somatostatin inhibitor, recombinant interleukin

For diagnostics

contrast media

Drugs found to have side effects and no longer used

Thalidomide, Diethylstilbestrol

Types of Pharmacological Preparations

Pharmaceuticals may be provided in a number of different pharmacology forms.Probably the most familiar are tablets and capsules, colloquially known as “pills”.

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